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KMID : 0604520070330010033
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Journal of the Society of Cosmetic Scientists of Korea
2007 Volume.33 No. 1 p.33 ~ p.40
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Anti-aging Effect of Astradalus membranaceus Root Extract
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Kim Mi-Jin
Lim Kyung-Ran
Jung Taek-Kyu
Yoon Kyung-Sup
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Abstract
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Astradalus membranaceus root extract (ARE) contains saponins, flavonoids, and their glycosides. Two flavonoids, calycosin and formononetin, were predominant constituents with the different amount by diverse extraction conditions. ARE showed the anti-oxidative activities, inhibited tyrosinase activity, and increased type I procollagen expression in proportion to calycosin and formononetin contents. The clinical study also showed that skin wrinkles were significantly reduced in the test group treated with a cream formulation containging 0.1% ARE compared with a group treated with a cream formulation without 0.1% ARE (p < 0.05). These results suggest that ARE may have potential as an anti-aging ingredient in cosmetics.
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KEYWORD
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Astradalus membranaceus root extract, calycosin, formononetin, anti-oxidative, tyrosinase activity, type I procollagen, anti-aging
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